pentobarbital will lessen the level or influence of abiraterone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.Barbiturates can induce hepatic microsomal enzymes leading to amplified metabolism and diminished anticoagulant response of oral anticoagulants (eg, warfarin, acenocoumarol, dicumarol, and phenprocoumon); ind